ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS INDUCE EXPANSION OF INTERLEUKIN-10-PRODUCING REGULATORY B CELLS AND AMELIORATE AUTOIMMUNITY IN A MURINE MODEL OF SYSTEMIC LUPUS ERYTHEMATOSUS

Mesenchymal stem cells (MSCs) are multipotent cells characterized by immunomodulatory properties and are therefore considered a promising tool for the Scent treatment of autoimmune diseases.One functional B-cell subset, regulatory B cells (Bregs), has recently been shown to restrain excessive inflammatory responses in autoimmune diseases.In the pre

Many teachers consider themselves digital immigrants who struggle to keep up with student digital natives.Whether or not this dichotomy still holds true, in a 21st Century context of teaching and learning, is debatable not least of all because of the exponential development of Outdoor Cooler apps and mobile learning technology.Nevertheless, it is s

Introduction: Different approaches to evaluating medical curriculum have been designed and implemented.The purpose of the present study is to review and analyze these approaches and, based on the Thien model, propose a framework for the evaluation and accreditation of the physiopathology curriculum for general physicians.Materials and Methods: This

Abstract Background While antibodies can provide significant protection from SARS-CoV-2 infection and disease sequelae, the specific attributes of the humoral response that contribute to immunity are incompletely defined.Methods We employ machine learning to relate characteristics of the polyclonal antibody response raised by natural infection to d

Adoption of proper Islamic law basis towards the concept of one who deserves to be killed and determining criminal sanctions in the case of crimes against one who allegedly deserves to be killed is significant both for the purpose of observing important principles of lawmaking and providing public order and security.Recent approach of criminal poli